Demons are supernatural enemies that can usually be found in underground places (mostly Cemetery Catacombs and Sister Ingrid's Mine) around Arizona and Oregon. They vary from vampire ghouls to rock-hard Gargoyles.
There are ten types of demons:
- Ghosts of the Fallen
- Giant Werewolves
- The Devil
- The Professor
- Vampire Outlaws
- All demon related missions (excluding La Grande Finale/La Grande Finale, Part 2 and the Professor's mission line) are played at nighttime in-game and underground. This may be because demons will burn in the daylight.
- The Android trailer shows a player killing demons in the day time in-game, but the demons would burn as they spawn at night.